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AleXo
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Prov.: Estero
Cittā: San Francisco, California
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 Inserito il - 07 febbraio 2012 : 18:47:42
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anche: "From all the different available formats, small immunoproteins (SIP) appear to offer the best compromise between stability, blood clearance and tumour accumulation [37,78,252]"
Ecco le referenze:
33. Hu, S., et al. Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts. Cancer Res 56, 3055-3061 (1996).
37. Borsi, L., et al. Selective targeting of tumoral vasculature: comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin. Int J Cancer 102, 75-85 (2002).
78. Schliemann, C. & Neri, D. Antibody-based vascular tumor targeting. Recent Results Cancer Res 180, 201-216 (2010).
252. Smith, K.A., et al. Demystified...recombinant antibodies. J Clin Pathol 57, 912-917 (2004). |
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minibody
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